Evidence map · SCS · painful diabetic neuropathy
SCS for painful diabetic neuropathy: what the research shows
10-kHz spinal cord stimulation for painful diabetic neuropathy. 291 papers from 1989 to 2026, including 10 meta-analyses, 21 systematic reviews and 29 randomised controlled trials. Each study below links to its source.
291Papers in the corpus
10Meta-analyses
29Randomised controlled trials
74Open-access papers
Study design
Jev labels59 papers have no confident study-design label yet. Labels are AI-classified by Jev: advisory, not clinician-reviewed.
Papers over time
by publication year* 2025–26 is still in progress, so its count is incomplete.
Most-cited trials and reviews
by citations- 1
Spinal cord stimulation in patients with painful diabetic neuropathy: a multicentre randomized clinical trial.
- 2
Effect of High-frequency (10-kHz) Spinal Cord Stimulation in Patients With Painful Diabetic Neuropathy: A Randomized Clinical Trial.
- 3
Electrical spinal-cord stimulation for painful diabetic peripheral neuropathy.
- 4
Spinal cord stimulation and pain relief in painful diabetic peripheral neuropathy: a prospective two-center randomized controlled trial.
- 5
Sustained Treatment Effect of Spinal Cord Stimulation in Painful Diabetic Peripheral Neuropathy: 24-Month Follow-up of a Prospective Two-Center Randomized Controlled Trial.
- 6
Long-term efficacy of high-frequency (10 kHz) spinal cord stimulation for the treatment of painful diabetic neuropathy: 24-Month results of a randomized controlled trial.
- 7
Evidence-Based Treatment of Painful Diabetic Neuropathy: a Systematic Review.
- 8
Quality of life increases in patients with painful diabetic neuropathy following treatment with spinal cord stimulation.
Recent trials and reviews
last 3 years- 1
High-Frequency 10-kHz Spinal Cord Stimulation Provides Long-term (24-Month) Improvements in Diabetes-Related Pain and Quality of Life for Patients with Painful Diabetic Neuropathy.
- 2
Therapeutic and Diagnostic Landscape of Diabetic Neuropathy: A Systematic Review of Clinical Studies.
- 3
Spinal Cord Stimulation Improves Pain and Quality of Life in Painful Diabetic Neuropathy: A Meta-Analysis of Randomized Trials.
- 4
Improvement in Protective Sensation: Clinical Evidence From a Randomized Controlled Trial for Treatment of Painful Diabetic Neuropathy With 10 kHz Spinal Cord Stimulation.
- 5
Assessing the Efficacy of Spinal Cord Stimulation in Managing Painful Diabetic Neuropathy: A Systematic Review and Meta-Analysis.
Decision support only. This page summarises published literature; it is not medical advice or a recommendation for any patient. Study designs and topic labels are AI-classified by Jev: advisory, not clinician-reviewed. Abstracts are not reproduced here: follow the links to read each source. Data snapshot 2026-09-25.