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Evidence map · DRG · CRPS and focal neuropathic pain

DRG for CRPS and focal neuropathic pain: what the research shows

Dorsal root ganglion stimulation for CRPS and focal neuropathic pain. 352 papers from 1976 to 2026, including 7 meta-analyses, 25 systematic reviews and 7 randomised controlled trials. Each study below links to its source.

352Papers in the corpus
7Meta-analyses
7Randomised controlled trials
93Open-access papers

Study design

Jev labels
Meta-analysis7Systematic review25RCT7Non-randomised trial30Cohort35Cross-sectional3Case series30Case report51

61 papers have no confident study-design label yet. Labels are AI-classified by Jev: advisory, not clinician-reviewed.

Papers over time

by publication year
230115 1975–792000–042025–26*

* 2025–26 is still in progress, so its count is incomplete.

Most-cited trials and reviews

by citations
  1. 1

    Dorsal root ganglion stimulation yielded higher treatment success rate for complex regional pain syndrome and causalgia at 3 and 12 months: a randomized comparative trial.

    RCTDeer et al. · 2017 · 378 citations · Open access
  2. 2

    Effectiveness and Safety of Dorsal Root Ganglion Stimulation for the Treatment of Chronic Pain: A Pooled Analysis.

    Meta-analysisHuygen FJPM et al. · 2020 · 53 citations · Open access
  3. 3

    Implanted spinal neuromodulation interventions for chronic pain in adults.

    Meta-analysisO'Connell et al. · 2021 · 43 citations
  4. 4

    Invasive Electrical Neuromodulation for the Treatment of Painful Diabetic Neuropathy: Systematic Review and Meta-Analysis.

    Meta-analysisRaghu et al. · 2021 · Neuromodulation : journal of the International Neuromodulation Society · 34 citations
  5. 5

    The Effectiveness of Various Types of Electrical Stimulation of the Spinal Cord for Chronic Pain in Patients with Postherpetic Neuralgia: A Literature Review.

    Systematic reviewIsagulyan et al. · 2023 · 29 citations · Open access
  6. 6

    Dorsal Root Ganglion Stimulation for the Treatment of Non-Complex Regional Pain Syndrome Related Chronic Pain Syndromes: A Systematic Review.

    Systematic reviewStelter et al. · 2021 · 13 citations
  7. 7

    Frequency dependency of therapeutic efficacy in dorsal root ganglion stimulation for neuropathic pain.

    RCTPiedade et al. · 2022 · 11 citations · Open access
  8. 8

    Painful Peripheral Neuropathies of the Lower Limbs and/or Lower Extremities Treated with Spinal Cord Stimulation: A Systematic Review with Narrative Synthesis.

    Systematic reviewBurkey et al. · 2023 · Journal of pain research · 10 citations · Open access

Recent trials and reviews

last 3 years
  1. 1

    Neurostimulation for the Treatment of Cancer-Induced Pain: A Scoping Review.

    Systematic reviewVu et al. · 2025 · 7 citations
  2. 2

    Anatomical and morphological variations in the dorsal root ganglion: Technical implications for chronic pain treatment with neuromodulation-A systematic review.

    Systematic reviewAcevedo-Gonzalez et al. · 2025 · 1 citations · Open access
  3. 3

    A scoping review of spinal cord stimulation for phantom limb pain.

    Systematic reviewJaffee et al. · 2025 · 1 citations · Open access
  4. 4

    Long-term efficacy of spinal cord stimulation for chronic primary neuropathic pain in the contemporary era: a systematic review and meta-analysis.

    Meta-analysisFatima et al. · 2024 · 5 citations
  5. 5

    Effectiveness of Dorsal Root Ganglion Stimulation in Chronic Pain Management: A Systematic Review.

    Systematic reviewCampos-Fajardo et al. · 2024 · 3 citations

Decision support only. This page summarises published literature; it is not medical advice or a recommendation for any patient. Study designs and topic labels are AI-classified by Jev: advisory, not clinician-reviewed. Abstracts are not reproduced here: follow the links to read each source. Data snapshot 2026-09-25.