Evidence map · HNS · obstructive sleep apnea
HNS for obstructive sleep apnea: what the research shows
Hypoglossal nerve stimulation for obstructive sleep apnea. 424 papers from 1995 to 2026, including 15 meta-analyses, 13 systematic reviews and 9 randomised controlled trials. Each study below links to its source.
424Papers in the corpus
15Meta-analyses
9Randomised controlled trials
116Open-access papers
Study design
Jev labels86 papers have no confident study-design label yet. Labels are AI-classified by Jev: advisory, not clinician-reviewed.
Papers over time
by publication year* 2025–26 is still in progress, so its count is incomplete.
Most-cited trials and reviews
by citations- 1
Hypoglossal nerve stimulation in the treatment of obstructive sleep apnea: A systematic review and meta-analysis.
- 2
Endotypic Mechanisms of Successful Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea.
- 3
The Hypoglossal Nerve Stimulation as a Novel Therapy for Treating Obstructive Sleep Apnea-A Literature Review.
- 4
Targeted Hypoglossal Nerve Stimulation for Patients With Obstructive Sleep Apnea: A Randomized Clinical Trial.
- 5
Evaluation of Hypoglossal Nerve Stimulation Treatment in Obstructive Sleep Apnea.
- 6
Hypoglossal nerve stimulation in adolescents with down syndrome and obstructive sleep apnea: A systematic review and meta-analysis.
- 7
Electrical stimulation as a therapeutic approach in obstructive sleep apnea - a meta-analysis.
- 8
Hypoglossal Nerve Stimulation and Cardiovascular Outcomes for Patients With Obstructive Sleep Apnea: A Randomized Clinical Trial.
Recent trials and reviews
last 3 years- 1
Two vs. Three Incisions for Hypoglossal Nerve Stimulator Implantation to Treat Sleep Apnea: A Systematic Review.
- 2
Subjective and objective measures of sleep-related function from the Cardiovascular Endpoints For Obstructive Sleep Apnea with Twelfth Cranial Nerve Stimulation (CARDIOSA-12) trial : Sleep-related functional outcomes in CARDIOSA-12.
- 3
Proximal Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea in the OSPREY Study : A Randomized Controlled Trial.
- 4
Hypoglossal Nerve Stimulation and Cardiovascular Outcomes for Patients With Obstructive Sleep Apnea: A Randomized Clinical Trial.
- 5
Hypoglossal nerve stimulation for obstructive sleep apnea in adults: An updated systematic review and meta-analysis.
Decision support only. This page summarises published literature; it is not medical advice or a recommendation for any patient. Study designs and topic labels are AI-classified by Jev: advisory, not clinician-reviewed. Abstracts are not reproduced here: follow the links to read each source. Data snapshot 2026-09-25.