Evidence map · DBS · treatment-refractory OCD
DBS for treatment-refractory OCD: what the research shows
Deep brain stimulation for treatment-refractory OCD. 1,171 papers from 1993 to 2026, including 34 meta-analyses, 54 systematic reviews and 24 randomised controlled trials. Each study below links to its source.
1,171Papers in the corpus
34Meta-analyses
24Randomised controlled trials
308Open-access papers
Study design
Jev labels289 papers have no confident study-design label yet. Labels are AI-classified by Jev: advisory, not clinician-reviewed.
Papers over time
by publication year* 2025–26 is still in progress, so its count is incomplete.
Most-cited trials and reviews
by citations- 1
Deep brain stimulation of the nucleus accumbens for treatment-refractory obsessive-compulsive disorder.
- 2
Deep brain stimulation for refractory obsessive-compulsive disorder.
- 3
Obsessive-Compulsive Disorder: Advances in Diagnosis and Treatment.
- 4
Deep brain stimulation for intractable obsessive compulsive disorder: pilot study using a blinded, staggered-onset design.
- 5
Deep Brain Stimulation for Obsessive-Compulsive Disorder: A Meta-Analysis of Treatment Outcome and Predictors of Response.
- 6
Unilateral deep brain stimulation of the nucleus accumbens in patients with treatment-resistant obsessive-compulsive disorder: Outcomes after one year.
- 7
Electrical stimulation in the bed nucleus of the stria terminalis alleviates severe obsessive-compulsive disorder.
- 8
A Randomized Trial Directly Comparing Ventral Capsule and Anteromedial Subthalamic Nucleus Stimulation in Obsessive-Compulsive Disorder: Clinical and Imaging Evidence for Dissociable Effects.
Recent trials and reviews
last 3 years- 1
Deep Brain Stimulation for the Treatment of Treatment-Resistant Obsessive-Compulsive Disorder: A Meta-Analysis of Randomized Clinical Trials in 106 Patients.
- 2
Deep Brain Stimulation for Refractory OCD and Depression: From Neurocircuitry to Personalised Neuromodulation.
- 3
Comparative efficacy and safety of different surgical strategies for refractory obsessive-compulsive disorder: evidence from network meta-analysis.
- 4
Circuit-based neuromodulation for obsessive-compulsive disorder: a systematic review, meta-analysis, and translational case study.
- 5
Deep brain stimulation for obsessive-compulsive-disorder: a systematic review and meta-analysis of individual participant outcome data from sham-controlled trials.
Decision support only. This page summarises published literature; it is not medical advice or a recommendation for any patient. Study designs and topic labels are AI-classified by Jev: advisory, not clinician-reviewed. Abstracts are not reproduced here: follow the links to read each source. Data snapshot 2026-09-25.