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Evidence map · SNM · bladder and bowel dysfunction

SNM for bladder and bowel dysfunction: what the research shows

Sacral neuromodulation for bladder and bowel dysfunction. 1,883 papers from 1971 to 2026, including 36 meta-analyses, 90 systematic reviews and 73 randomised controlled trials. Each study below links to its source.

1,883Papers in the corpus
36Meta-analyses
73Randomised controlled trials
311Open-access papers

Study design

Jev labels
Meta-analysis36Systematic review90RCT73Non-randomised trial222Cohort278Case-control2Cross-sectional28Case series27

427 papers have no confident study-design label yet. Labels are AI-classified by Jev: advisory, not clinician-reviewed.

Papers over time

by publication year
460230 1970–741995–992025–26*

* 2025–26 is still in progress, so its count is incomplete.

Most-cited trials and reviews

by citations
  1. 1

    Sacral nerve stimulation for treatment of refractory urinary urge incontinence. Sacral Nerve Stimulation Study Group.

    RCTSchmidt et al. · 1999 · 259 citations
  2. 2

    Efficacy of sacral nerve stimulation for urinary retention: results 18 months after implantation.

    RCTJonas et al. · 2001 · 200 citations
  3. 3

    Efficacy of sacral nerve stimulation for fecal incontinence: results of a multicenter double-blind crossover study.

    RCTLeroi et al. · 2005 · 164 citations
  4. 4

    Systematic review of sacral nerve stimulation for faecal incontinence and constipation.

    Systematic reviewJarrett et al. · 2004 · 153 citations
  5. 5

    Sacral nerve stimulation is more effective than optimal medical therapy for severe fecal incontinence: a randomized, controlled study.

    RCTTjandra et al. · 2008 · 151 citations
  6. 6

    OnabotulinumtoxinA vs Sacral Neuromodulation on Refractory Urgency Urinary Incontinence in Women: A Randomized Clinical Trial.

    RCTAmundsen et al. · 2016 · 147 citations
  7. 7

    Systematic review of the clinical effectiveness of neuromodulation in the treatment of faecal incontinence.

    Systematic reviewThin et al. · 2013 · 133 citations
  8. 8

    Efficacy and safety of sacral nerve stimulation for urinary urge incontinence: a systematic review.

    Systematic reviewBrazzelli et al. · 2006 · 129 citations

Recent trials and reviews

last 3 years
  1. 1

    Exploratory Analysis of Urinary and Sexual Dysfunction in Patients With Low Anterior Resection Syndrome Undergoing Sacral Neuromodulation: Insights From the SANLARS Trial.

    RCTMarinello et al. · 2026 · 1 citations
  2. 2

    Urethrogenic Overactive Bladder: A Systematic Review of Pathophysiological Mechanisms and Clinical Implications

    Systematic reviewRosato et al. · 2026 · 0 citations
  3. 3

    Efficacy of Sacral Neuromodulation in Treatment of Fecal Incontinence Associated With Anal Sphincter Defects: A Systematic Review and Meta-Analysis.

    Meta-analysisEmile et al. · 2026 · 0 citations
  4. 4

    Efficacy and Safety of Sacral Neuromodulation on Patients With Multiple Sclerosis and Lower Urinary Tract Dysfunction: A Systematic Review and Meta-Analysis.

    Meta-analysisFerreira et al. · 2026 · 0 citations · Open access
  5. 5

    Long-term Outcomes of Sacral Nerve Stimulation on the Treatment of Fecal Incontinence: A Systematic Review.

    Systematic reviewEggers et al. · 2025 · 5 citations

Decision support only. This page summarises published literature; it is not medical advice or a recommendation for any patient. Study designs and topic labels are AI-classified by Jev: advisory, not clinician-reviewed. Abstracts are not reproduced here: follow the links to read each source. Data snapshot 2026-09-25.