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Evidence map · PBM · Alzheimer’s disease and MCI

PBM for Alzheimer’s disease and MCI: what the research shows

Photobiomodulation for Alzheimer’s disease and MCI. 77 papers from 2016 to 2026, including 1 meta-analyses, 8 systematic reviews and 13 randomised controlled trials. Each study below links to its source.

77Papers in the corpus
1Meta-analyses
13Randomised controlled trials
57Open-access papers

Study design

Jev labels
Meta-analysis1Systematic review8RCT13Non-randomised trial1Cross-sectional1Narrative review22Animal study8In-vitro study1

21 papers have no confident study-design label yet. Labels are AI-classified by Jev: advisory, not clinician-reviewed.

Papers over time

by publication year
2513 201620212026*

* 2026 is still in progress, so its count is incomplete.

Most-cited trials and reviews

by citations
  1. 1

    Photobiomodulation and visual stimulation against cognitive decline and Alzheimer's disease pathology: A systematic review.

    Systematic reviewMonteiro et al. · 2022 · 14 citations · Open access
  2. 2

    Phototherapy for Cognitive Function in Patients With Dementia: A Systematic Review and Meta-Analysis.

    Meta-analysisZhu et al. · 2022 · 13 citations · Open access
  3. 3

    Can transcranial photobiomodulation improve cognitive function in TBI patients? A systematic review.

    Systematic reviewZeng et al. · 2024 · 7 citations · Open access
  4. 4

    The effect of transcranial photobiomodulation on cognitive function and attentional performance of older women with mild cognitive impairment: a randomized controlled trial.

    RCTPapi et al. · 2022 · 6 citations · Open access
  5. 5

    The Efficacy and Safety of Transcranial Photobiomodulation for Mild Cognitive Impairment Due to Alzheimer's Disease: A Randomized, Double-Blind, Sham-Controlled Study.

    RCTChun et al. · 2025 · 2 citations

Recent trials and reviews

last 3 years
  1. 1

    The Efficacy and Safety of Transcranial Photobiomodulation for Mild Cognitive Impairment Due to Alzheimer's Disease: A Randomized, Double-Blind, Sham-Controlled Study.

    RCTChun et al. · 2025 · 2 citations
  2. 2

    Can transcranial photobiomodulation improve cognitive function in TBI patients? A systematic review.

    Systematic reviewZeng et al. · 2024 · 7 citations · Open access

Decision support only. This page summarises published literature; it is not medical advice or a recommendation for any patient. Study designs and topic labels are AI-classified by Jev: advisory, not clinician-reviewed. Abstracts are not reproduced here: follow the links to read each source. Data snapshot 2026-09-25.